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70-0011-HER2-CISH-Stained-breast-cancer-X40-3

In Situ Hybridization (CISH) Kit HER2 Chromogenic

Sakura Finetek

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Genemed HER2 CISH Kit is intended to detect HER2 gene amplification in

formalin-fixed, paraffin-embedded (FFPE) tissue sections using Chromogenic In

Situ Hybridization.

The human gene HER2, or c-erbB-2, and the rat equivalent gene, neu, have

been identified as proto-oncogenes sharing homology with the closely related

v-erbB oncogene. The HER2 gene is located on chromosome 17 (17q12-21) and

encodes a 185 kDa membrane receptor-like protein. HER2 has tyrosine kinase

activity and shares homology with, but is distinct from, the epidermal growth factor

receptor (known as EGFr, HER1, or c-erbB-1).

Genemed HER2 Probe (Reagent C) is a double-stranded DNA probe that has

been labeled with digoxigenin. It is supplied in a liquid format in hybridization

buffer. It has been demonstrated to contain the HER2 gene by PCR, and to bind

specifically to the HER2 gene locus on chromosome 17q12-21 by metaphase

FISH in normal lymphocytes.

No. of Tests: 20 (20 μL probe per test) Catalog No.: 80-0001

Intended Use: USA RUO, CE IVD

  • Topaz.Bar-Gil@Perrigo.co.il

In Situ Hybridization (CISH) Kit HER2 Chromogenic